منابع مشابه
In silico veritas
Literacy underpins constitutions, civil rights and liberties. But E-mail is replacing the letter; the digital certificate, the written signature. Printing allows the recording and dissemination of observations, thoughts and ideas. But the Internet is competing with the printed page; the searchable database with the index of contents. If you are reading this article online, you may have retrieve...
متن کامل[Ex vivo veritas].
427 LE P OI NT D E VU E DE S IR IU S FO RU M Ayant eu le privilège d’assister au Symposium International sur les cellules ES humaines (FISH-ESC) organisé par Marc Peschanski (Genocentre d’Évry, 31 janvier-2 février 2008) (➜), je voudrais le replacer dans le contexte de la révolution de la biologie moléculaire et de son impact médical. La plupart des gènes de maladies humaines et leurs mutations...
متن کاملSolid-Phase Environmental Genotoxicity: In Vivo Veritas!
Specific genotoxicity of solid particles are discussed by using three different examples. Carcinogenic asbestos fibres have primary genotoxic effects as well, that can be studied in in vitro studies. Nevertheless, demonstration of their mesothelioma inducing effect is only possible in in vivo studies. Their carrier function seems to be essential for the biological activity. Carbon nanotubes do ...
متن کاملMacrophage plasticity and polarization: in vivo veritas.
Diversity and plasticity are hallmarks of cells of the monocyte-macrophage lineage. In response to IFNs, Toll-like receptor engagement, or IL-4/IL-13 signaling, macrophages undergo M1 (classical) or M2 (alternative) activation, which represent extremes of a continuum in a universe of activation states. Progress has now been made in defining the signaling pathways, transcriptional networks, and ...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 1999
ISSN: 1087-0156,1546-1696
DOI: 10.1038/9833